The initial sketch, just to get the idea down:
I draw the design in pencil on A3, then ink it with a cheap fineliner, then erase the pencil lines and then ink it with my brush-pen. Doing it this way round ensures that I'm not erasing over my final inks, so they stay nice and opaque.
My trusty Pentel Pocket Brush:
I scan in the design, convert the lines to vector, and work on colours and arrangement using my Wacom tablet in Photoshop. When I'm happy, I produce the colour seperations which are sent to the printer for outputting onto clear acetate. These are then used to create the screens used to print each of the four colours:
The gold screen, taped and ready for ink:
Printing the red:
Closeup of the key screen: